The Princess Margaret Cancer Foundation has received a $100-million donation, the largest single gift for cancer care in Canadian history, from a donor who has chosen to remain anonymous.
The gift was announced Tuesday night at the launch of Carry the Fire, a $2.5-billion multi-year fundraising campaign meant to accelerate cancer research, treatment and care. Dr. Keith Stewart, director of the Princess Margaret Cancer Centre, said he learned of the donation during a routine meeting and described it as “a lovely surprise.”
Unlike many major gifts, the donation was not directed toward a specific program. The donor, who has a personal connection to cancer, left it to the centre to decide how the funds should be used, giving Princess Margaret flexibility to put the money toward its top priorities: early cancer detection, speeding up new treatments, and improving patient care.
Unrestricted Funding a Rarity
Miyo Yamashita, president and CEO of the Princess Margaret Cancer Foundation, delivered the news of the gift to Stewart. She said gifts of this scale are almost never given without conditions attached, and that anonymous donations at any level are uncommon in the philanthropic world.
Yamashita said unrestricted funding allows the centre to take bigger risks in pursuit of major breakthroughs for cancer patients, rather than limiting spending to a narrowly defined project.

Rising Costs of Cancer Research
Princess Margaret treats about 21,000 new cancer patients each year and supports roughly 2,000 researchers along with hundreds of clinical trials aimed at improving early detection and treatment outcomes. Stewart said the scale of that work means funding needs can escalate quickly.
On the same morning the $100-million gift was announced internally, Stewart said he was separately involved in discussions about a proposed $15-million early detection clinic that would regularly screen people at high risk of cancer due to family history or genetic mutations, as well as a new drug that requires $5 million in additional funding before it can move into clinical trials.
Stewart noted that hospital operating budgets from government funding do not directly cover this kind of research and development work, meaning the centre depends on philanthropic support to advance both research and its translation into patient care.
Princess Margaret Cancer Foundation Funding Figures
The $100-million donation was announced as part of the broader Carry the Fire campaign, which the foundation describes as an effort to work toward a future free from the fear of cancer. Yamashita said the day the gift was confirmed stood out among the more difficult days that come with fundraising for cancer care, describing the relief and emotion tied to understanding the impact the funding could have for patients and their families.
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